Genomics And Proteonomics Assignment Help

Genomics And Proteonomics

Thomas H. Roderick coined the term genomics which now includes sequencing of genomes, determination of the complete set of proteins encoded by an organism, and the functioning of genes and metabolic pathways in an organism. Genomics deals not only with the determination of the genetic information present in an organism but also with understanding the mechanism by which this information is used by the organism. An enormous amount of information is generated in genomics which needs the powerful computers and specific software for its interpretation and management. The two major domains of genomics are:

i) Structural genomics: it deals with the determination of the complete sequence of genomes or the complete set of proteins produced by an organism. This is executed by construction of high resolution genetic and physical maps, sequencing the genome and the determination of the complete set of proteins in an organism

ii) Functional genomics: It studies the functioning of genes and metabolic pathways, i.e. the gene expression patterns in an organism.

The main topics which are considered in Genomics And Proteonomics are discussed in brief as follows:

1. Sequencing of Genomes
2. Comparative Genomics
3. Gene Prediction And Counting
4. Genome Evolution And Functional Genomics
5. Expression profiling And Transcriptome
6. DNA Arrays
7. Structural proteomics And Functional Proteomics
8. Expression Proteomics And Sequence Allgnment
9. Protein Structure And Structure And Structural Analysis
10. Two-Dimensional Electrophoresis And Domain Fusion Method

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